Thulium Laser Combined with PDRN: A Promising Solution for Pattern Hair Loss

Sep 22, 2025

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Pattern hair loss (PHL) is one of the most common conditions affecting both men and women. It is characterized by the gradual thinning of hair, which can significantly impact confidence and quality of life. Traditional treatments for PHL include oral medications such as finasteride or dutasteride, topical agents like minoxidil, hair transplantation, platelet-rich plasma (PRP) injections, and the use of tissue activators and antioxidants such as PDRN, placental extract, zinc sulfate, biotin, and niacinamide.

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In recent years, laser technology has emerged as an effective additional or alternative treatment for hair loss. Clinical studies show that fractional lasers improve blood supply to hair follicles, stimulate signaling molecules, and promote the release of growth factors-helping restore thicker and healthier hair.

Clinical Study: 1927nm Thulium Laser Combined with PDRN

A recent clinical evaluation investigated the efficacy of 1927nm fractional thulium laser combined with PDRN injections for the treatment of pattern hair loss. Sixteen Korean patients with PHL (12 men and 4 women, aged 26–46) were divided into two groups:

Group 1: Received 12 weekly sessions of thulium laser treatment combined with follicular PDRN injections.

Group 2: Received 12 weekly sessions of mesotherapy combined with PDRN injections.

Results

Hair Count Improvement:

Group 1 (Thulium Laser + PDRN): 20.4% increase in average hair count (p=0.005).

Group 2 (Mesotherapy + PDRN): 9.7% increase in hair count (p=0.007).

Hair Thickness Improvement:

Group 1: 53.1% improvement in hair thickness (p<0.001).

Group 2: 16.1% improvement in hair thickness (p<0.05).

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Notably, the thulium laser group achieved significantly greater improvement in hair thickness compared to mesotherapy (p=0.029).

Treatment Safety and Comfort

Each thulium laser session lasted less than 5 minutes. Patients reported good tolerability, with only temporary redness and mild discomfort. The combination of 1927nm thulium laser and PDRN injections proved to be a safe, efficient, and clinically effective approach for increasing both hair density and diameter.

Why Choose a Thulium Laser for Hair Loss Treatments?

The 1927nm wavelength penetrates effectively into the scalp, stimulating follicle regeneration and enhancing the absorption of growth factors like PDRN. This dual approach not only revives dormant follicles but also strengthens existing hair, providing long-lasting results with minimal downtime.

Recommended Device: Newangie Thulium Laser Machine

At Newangie, we specialize in professional beauty and medical equipment. Our Thulium Laser Machine is designed for safe, fast, and effective treatments for hair loss, skin rejuvenation, and more. With advanced technology, user-friendly operation, and reliable performance, it is the ideal choice for clinics and beauty centers looking to expand their treatment portfolio.

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